MEGIN Masterclass

Electromagnetic Source Imaging in the Presurgical Evaluation of Children with Drug Resistant Epilepsy

Presented by Dr. Christos Papadelis.

Abstract: “Non-invasive diagnostic tools, such as magnetoencephalography (MEG) and high-density electroencephalography (HD-EEG), are becoming of high importance in the presurgical evaluation of patients with drug resistant epilepsy (DRE). These tools have different sensitivity profiles for detecting and localizing epileptiform foci. MEG has higher spatial resolution for sources that are tangential to the plane of the cortical surface, but it is almost blind to radially oriented sources and sources from deep brain areas. Contrarily, HD-EEG can detect and localize both radially oriented as well as tangentially oriented sources. Despite their complementary properties, MEG and HD-EEG are rarely recorded simultaneously or analyzed into a combined source imaging solution. In this talk, Dr. Papadelis will talk about the accuracy and clinical utility of combined electromagnetic source imaging in localizing interictal epileptiform discharges and predict surgical outcome in children with DRE.”

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**TRIUX™ neo is intended to non-invasively record brain activity, and when interpreted by trained physicians, to help localize these active areas. All other applications are scientific research in nature. Please contact MEGIN for further information.