Page 199 - MEGIN Book Of Abstracts - 2023

temporal and parietal lobes as well as motor-related re- Sensitivity of magnetoencephalography as a
gions of precentral/premotor and postcentral/somato- diagnostic tool for epilepsy: a prospective study
motor gyri. A region-of-interest analysis of ADN and PN (2020)
suggested a strong correlation of r = 0.74 (p < 0.05, FDR
corrected) between the two tasks within the language- Koster, Imte; Ossenblok, Pauly; Brekelmans, Geert J; van
related brain regions, with the highest spatial overlap in der Linden, Inge; Hillebrand, Arjan; Wijnen, Ben Fm;
the prefrontal areas. Laterality indices (LIs) consistently Colon, Albert J
showed left dominance (LI > 0.1) for most individuals
(93% and 82% during ADN and PN, respectively), with Department of Clinical Neurophysiology, Academic Centre
average LIs of 0.40 ± 0.25 and 0.34 ± 0.20 for ADN and for Epileptology, Kempenhaeghe / MUMC+, Heeze, in col-
PN, respectively. Source analysis of task-related beta laboration with Faculty of Health, Medicine & Life Sciences,
power decrements appears to be a reliable method for Maastricht University, Maastricht; Department of Clinical
lateralizing and localizing brain activations associated Neurophysiology, Academic Centre for Epileptology, Kem-
with language processing in patients with epilepsy. penhaeghe / MUMC+, Heeze,, Biomedical Image Analysis,
BioMedical Technology, Eindhoven University of Technology,
Keywords: Auditory description naming (ADN), DICS Eindhoven; Department of Neurology and Clinical Neuro-
beamformer, Magnetoencephalography (MEG), Presurgi- physiology, Elisabeth-Twee Steden Hospital, Tilburg; Depart-
cal language mapping, Visual picture naming (PN) ment of Clinical Neurophysiology and MEG Centre, Amster-
dam Neuroscience, Amsterdam University Medical Centre,
NeuroImage (2020), Vol. 220 (32593799) (9 citations) Vrije Universiteit Amsterdam, Amsterdam; Department of
Public Mental Health, Centre for Economic Evaluations,
Trimbos Institute (Netherlands Institute of Mental Health and
Relationship between epileptiform discharges and Addiction), Utrecht,, Department of Health Services Research,
social reciprocity or cognitive function in children CAPHRI School of Public Health and Primary Care, Maastricht
with and without autism spectrum disorders: An University, Maastricht, The Netherlands
MEG study (2020)
ABSTRACT The diagnostic process for epilepsy can
Hirosawa, Tetsu; Sowman, Paul F; Fukai, Mina; Kameya, be lengthy and stressful, which may delay the start of
Masafumi; Soma, Daiki; Hino, Shoryoku; Kitamura, treatment. The objective of this study was to determine
Tatsuru; An, Kyung-Min; Yoshimura, Yuko; Hasegawa, the benefit of routine magnetoencephalography (MEG)
Chiaki; Saito, Daisuke; Ikeda, Takashi; Kikuchi, Mitsuru with regard to diagnostic gain, compared to routine
electroencephalography (EEG), EEG following sleep
Department of Psychiatry and Neurobiology, Graduate deprivation (EEGsd), and 24-hour EEG. In this prospec-
School of Medical Science, Kanazawa University, Kanazawa, tive study, patients were included from two centres
Japan; Department of Cognitive Science, Australian Hearing (Academic Centre for Epileptology Kempenhaeghe,
Hub, Macquarie University, Sydney, Australia; Department of Heeze and Elisabeth-Twee Steden Hospital, Tilburg)
Neuropsychiatry, Ishikawa Prefectural Takamatsu Hospital, and MEG recording took place at a single centre (Am-
Kahoku, Japan; Research Center for Child Mental Develop- sterdam University Medical Centre, Vrije Universiteit
ment, Kanazawa University, Kanazawa, Japan; Faculty of Amsterdam) in The Netherlands. Consecutively referred
Education, Institute of Human and Social Sciences, Kanaza- patients from peripheral hospitals were included
wa University, Kanazawa, Japan between August 2013 and March 2016. Patients were
offered routine MEG in addition to EEG examination
Psychiatry and clinical neurosciences (2020), Vol. 74, No. 9 and MRI for the diagnosis of epilepsy. The final clinical
(32588484) (1 citation) diagnosis was based on all available clinical data and
test results at the end of the diagnostic process. Sensi-
tivity, specificity, and positive and negative predictive

 ontents  Index 178
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