Page 300 - MEGIN Book Of Abstracts - 2023

Stroke

Time course of right-hemisphere recruitment neural responses were supported by the right hemi-
during word production following left-hemisphere sphere, compared to the typical left-lateralised brain re-
damage: A single case of young stroke (2022) sponse of a matched control. Differential recruitment of
right-hemisphere structures (330-440 ms post-picture
Chupina, Irina; Sierpowska, Joanna; Zheng, Xiaochen Y; onset) was found concurrently during successful nam-
Dewenter, Anna; Piastra, Maria-Carla; Piai, Vitória ing (right mid-to-posterior temporal lobe) and word-
finding attempts (right inferior frontal gyrus). Discon-
Donders Centre for Cognition, Radboud University, Nijmegen, nection of the temporal lobes via corpus callosum was
The Netherlands; Cognition and Brain Plasticity Unit, Depart- not critical for recruitment of the right hemisphere in
ment of Cognition, Development and Educational Psychol- visually guided naming, possibly due to neural activ-
ogy, Institut de Neurociències, Universitat de Barcelona, ity right lateralising from the outset. Although J.'s right
Barcelona, Spain; Donders Centre for Cognitive Neuroimag- hemisphere responded in a timely manner during word
ing, Radboud University, Nijmegen, The Netherlands; Institute planning, its lexical and phonological retrieval abilities
for Stroke and Dementia Research (ISD), University Hospital, remained modest.
LMU Munich, Munich, Germany; Clinical Neurophysiology,
Technical Medical Centre, Faculty of Science and Technology, Keywords: alpha oscillations, beta oscillations, event-relat-
University of Twente, Enschede, The Netherlands; Department ed fields, language lateralisation, splenium
of Medical Psychology, Donders Centre for Medical Neuro-
science, Radboud University Medical Center, Nijmegen, The The European journal of neuroscience (2022), Vol. 56, No.
Netherlands 8 (36028218) (1 citation)

ABSTRACT Our understanding of post-stroke lan-
guage function is largely based on older age groups, Electrophysiological connectivity markers of
who show increasing age-related brain pathology preserved language functions in post-stroke
and neural reorganisation. To illustrate language aphasia (2022)
outcomes in the young-adult brain, we present the
case of J., a 23-year-old woman with chronic aphasia Shah-Basak, Priyanka; Sivaratnam, Gayatri; Teti, Selina;
from a left-hemisphere stroke affecting the temporal Deschamps, Tiffany; Kielar, Aneta; Jokel, Regina;
lobe. Diffusion MRI-based tractography indicated that Meltzer, Jed A
J.'s language-relevant white-matter structures were
severely damaged. Employing magnetoencephalogra- Rotman Research Institute, Baycrest Health Sciences, Toronto,
phy (MEG), we explored J.'s conceptual preparation and ON, Canada; Canadian Partnership for Stroke Recovery,
word planning abilities using context-driven and bare Ottawa, ON, Canada. Electronic address: prishah@mcw.edu;
picture-naming tasks. These revealed naming deficits, Department of Speech, Language, and Hearing Sciences,
manifesting as word-finding difficulties and semantic University of Arizona, Tucson, AZ, USA; Rotman Research
paraphasias about half of the time. Naming was how- Institute, Baycrest Health Sciences, Toronto, ON, Canada; Ca-
ever facilitated by semantically constraining lead-in nadian Partnership for Stroke Recovery, Ottawa, ON, Canada;
sentences. Altogether, this pattern indicates disrupted Department of Speech-Language Pathology, University of
lexical-semantic and phonological retrieval abilities. Toronto, Toronto, ON, Canada; Rotman Research Institute,
MEG revealed that J.'s conceptual and naming-related Baycrest Health Sciences, Toronto, ON, Canada; Canadian

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