Page 222 - MEGIN Book Of Abstracts - 2023

negative correlation with the network parameters in The source-based oscillatory dynamics of the pain-re-
certain frequency ranges. lated cortical regions, which comprises 10 node regions
(the bilateral primary [SI] and secondary somatosen-
CONCLUSIONS The results suggested that the individ- sory cortices, insula, medial frontal cortex, and anterior
uals with migraine showed deviant effective connectiv- cingulate cortex [ACC]), were calculated to determine
ity in viewing the human facial expressions in multi- the intrinsic connectivity and node strength at 1 to
frequencies. The prefrontal-temporal pathway might be 40 Hz. The total node strength within the pain-related
related to the altered negative emotional modulation cortical regions was smaller in the beta band in patients
in migraine. These findings suggested that migraine with migraine (70 EM and 80 CM) than in controls (n =
might be characterized by more universal altered ce- 65). In the beta band, the node strength and functional
rebral processing of negative stimuli. Since the signifi- connectivity values of patients with CM and patients
cant result in this study was frequency-specific, more with EM differed from those of controls in specific corti-
independent replicative studies are needed to confirm cal areas, notably the left SI (EM < control) and bilateral
these results, and to elucidate the neurocircuitry under- ACC (CM < control); moreover, the node strength was
lying the association between migraine and emotional lower in patients with CM than in those with EM. In
conditions. all patients with migraine, negative correlations were
observed between headache frequency and node
Keywords: Effective connectivity, Emotional stimuli, Mag- strength in the bilateral ACC. In conclusion, migraine is
netoencephalography, Migraine, Multi-frequency characterized by reduced beta oscillatory connectivity
within the pain-related cortical regions. Reduced beta
The journal of headache and pain (2022), Vol. 23, No. 1 connectivity in the ACC is linked to migraine chronifica-
(35032999) (1 citation) tion. Longitudinal studies should verify whether this
oscillation change is a brain signature and a potential
neuromodulation target for migraine.
Migraine chronification is associated with beta-
band connectivity within the pain-related cortical Pain (2021), Vol. 162, No. 10 (34534180) (6 citations)
regions: a magnetoencephalographic study (2021)

Hsiao, Fu-Jung; Chen, Wei-Ta; Liu, Hung-Yu; Wang, Yen- Brain Excitability in Tension-Type Headache: a
Feng; Chen, Shih-Pin; Lai, Kuan-Lin; Hope Pan, Li-Ling; Separate Entity from Migraine? (2021)
Coppola, Gianluca; Wang, Shuu-Jiun
Chen, Wei-Ta; Hsiao, Fu-Jung; Wang, Shuu-Jiun
Brain Research Center, National Yang-Ming University, Taipei,
Taiwan; Department of Neurology, Neurological Institute, Department of Neurology, Neurological Institute, Taipei
Taipei Veterans General Hospital, Taipei, Taiwan; Department Veterans General Hospital, No. 201, Sec. 2 Shih-Pai Rd, Taipei,
of Medico-Surgical Sciences and Biotechnologies, Sapienza Taiwan. [email protected]; Brain Research Center,
University of Rome Polo Pontino, Latina, Italy National Yang-Ming University, Taipei, Taiwan

ABSTRACT Pain disorders are associated with aber- PURPOSE OF REVIEW Tension-type headache is often
rant oscillations in the pain-related cortical regions; regarded as the "normal" headache due to its high
however, few studies have investigated the relationship prevalence and mild disability in contrast with mi-
between the functional cortical network and migraine graine. Clinically, both headaches are common comor-
chronification through direct neural signals. Magneto- bidities to each other. To date there has been many
encephalography was used to record the resting-state studies linked migraine to a brain excitability disorder.
brain activity of healthy controls as well as patients This review summarized earlier studies on brain excit-
with episodic migraine (EM) and chronic migraine (CM). ability of TTH and discuss if TTH is a separate clinical

 ontents  Index 201
C