Page 153 - MEGIN Book Of Abstracts - 2023

compared with the healthy participants, potentially Beijing City Key Lab for Medical Physics and Engineering,
improving the discrimination of epilepsy. Institution of Heavy Ion Physics, School of Physics, Peking Uni-
versity, Beijing 100871, China; Center for MRI Research, Acade-
Keywords: autodiagnosis, deep learning, epilepsy, magne- my for Advanced Interdisciplinary Studies, Peking University,
toencephalography, phase–amplitude coupling Beijing 100871, China; Center for MRI Research, Academy for
Advanced Interdisciplinary Studies, Peking University, Beijing
Journal of neural engineering (2022), Vol. 19, No. 2 100871, China; McGovern Institute for Brain Research, Peking
(35385832) (1 citation) University, Beijing 100871, China; Department of Neurosur-
gery, Sanbo Brain Hospital of Capital Medical University,
Beijing 100093, China; Center for MRI Research, Academy for
Prediction of seizure outcome following temporal Advanced Interdisciplinary Studies, Peking University, Beijing
lobectomy: A magnetoencephalography-based 100871, China; Laboratory of Applied Brain and Cognitive
graph theory approach" (2022) Sciences, College of International Business, Shanghai Inter-
national Studies University, Shanghai 201620, China; Beijing
Mukherjee, Joydeep; Kenchaiah, Raghavendra; City Key Lab for Medical Physics and Engineering, Institution
Gautham, Bhargava K; Narayanan, Chitra; Afsar, of Heavy Ion Physics, School of Physics, Peking University,
Mohammed; Narayanan, Mariyappa; Rajeswaran, Beijing 100871, China; Center for MRI Research, Academy for
Jamuna; Asranna, Ajay; Mundlamuri, Ravindranadh C; Advanced Interdisciplinary Studies, Peking University, Beijing
Viswanathan, Lakshminarayanapuram G; Mahadevan, 100871, China; McGovern Institute for Brain Research, Peking
Anita; Sadashiva, Nishanth; Arivazhagan, A; Karthik, K; University, Beijing 100871, China; National Biomedical Imag-
Bharath, Rose D; Saini, Jitendra; Kandavel, Thennarasu; ing Center, Peking University, Beijing 100871, China. Electronic
Rao, Malla Bhaskara; Sinha, Sanjib address: [email protected]

Department of Neurology, NIMHANS, Hosur road, Bangalore. ABSTRACT Determining the accurate locations of
India; Department of Neurology, NIMHANS, Hosur road, interictal spikes has been fundamental in the presurgi-
Bangalore. India; MEG research Centre, NIMHANS, Hosur cal evaluation of epilepsy surgery. Stereo-electroen-
Road, Bangalore, India; Department of Clinical Psychology, cephalography (SEEG) is able to directly record cortical
NIMHANS, Hosur road, Bangalore, India; Department of activity and localize interictal spikes. However, the main
Neuropathology, NIMHANS, Hosur road, Bangalore, India; caveat of SEEG techniques is that they have limited
Department of Neurosurgery, NIMHANS, Hosur road, Banga- spatial sampling (covering <5% of the whole brain),
lore, India; Department of Neuroimaging and Interventional which may lead to missed spikes originating from brain
Radiology, NIMHANS, Hosur road, Bangalore, India; Depart- regions that were not covered by SEEG. To address this
ment of Biostatistics, NIMHANS, Hosur road, Bangalore, India; problem, we propose a SEEG-informed minimum-norm
Department of Neurology, NIMHANS, Hosur road, Bangalore. estimates (SIMNE) method by combining SEEG with
India; MEG research Centre, NIMHANS, Hosur Road, Banga- magnetoencephalography (MEG) or EEG. Specifically,
lore, India. Electronic address: [email protected] the spike locations determined by SEEG offer as a priori
information to guide MEG source reconstruction. Both
Seizure (2022), Vol. 97 (35344920) (0 citations) computer simulations and experiments using data from
five epilepsy patients were conducted to evaluate the
performance of SIMNE. Our results demonstrate that
Informed MEG/EEG source imaging reveals the SIMNE generates more accurate source estimation than
locations of interictal spikes missed by SEEG (2022) a traditional minimum-norm estimates method and
reveals the locations of spikes missed by SEEG, which
Shu, Su; Luo, Shen; Cao, Miao; Xu, Ke; Qin, Lang; Zheng, would improve presurgical evaluation of the epilepto-
Li; Xu, Jing; Wang, Xiongfei; Gao, Jia-Hong genic zone.

 ontents  Index 132
C