Page 185 - MEGIN Book Of Abstracts - 2023

significant z-score clusters found 1 true-positive result lographic (MEG) recording were acquired before and
that was missed by qualitative analysis and 3 additional after the first and the last SCB session. For each record-
false-positive results (sensitivity 100%, specificity 23%). ing we computed the mean weighted phase lag index
(WPLI) across all pair of MEG sensors. After SCB, two
CONCLUSIONS ASL supports the hypothesis regarding patients had consistent reduction of seizure frequency
the EZ in poorly defined focal epilepsy cases in chil- (>50 %). Connectivity analysis revealed a decrease of
dren. Due to its convenience and noninvasive nature, WPLI-beta band in the two responders and an increase
the authors recommend that ASL be added routinely of WPLI-alpha connectivity in all patients regardless
to the presurgical MRI evaluation of epilepsy. Future of the clinical effect. Results suggest that reduction of
optimized quantitative methods may improve the diag- WPLI-beta-low connectivity is related to the clinical
nostic yield of this technique. response after SCB.

Keywords: epilepsy surgery, perfusion MRI, presurgical Keywords: Biofeedback, Connectivity, Epilepsy, Magneto-
evaluation encephalography, Phase-Lag-Index

Journal of neurosurgery. Pediatrics (2020), Vol. 27, No. 3 Epilepsy research (2021), Vol. 169 (33360538) (3 citations)
(33361483) (8 citations)

Reinterpretation of magnetic resonance imaging
Is beta band desynchronization related to skin findings with magnetoencephalography can
conductance biofeedback effectiveness in drug improve the accuracy of detecting epileptogenic
resistant focal epilepsy? (2021) cortical lesions (2021)

Ferri, Lorenzo; Chen, Sophie; Kotwas, Iliana; Giusiano, Otsuka, Kosuke; Egawa, Kiyoshi; Fujima, Noriyuki;
Bernard; Pizzo, Francesca; Roehri, Nicolas; Colombet, Kudo, Kohsuke; Terae, Satoshi; Nakajima, Midori; Ito,
Bruno; Bénar, Christian-George; Bartolomei, Fabrice Tomoshiro; Yagyu, Kazuyori; Shiraishi, Hideaki

IRCCS Bologna Institute of Neurological Sciences, Bologna, Department of Pediatrics, Hokkaido University Graduate
Italy; Department of Biomedical and Neuromotor Sciences, School of Medicine, North 15, West 7, Kita-ku, Sapporo, Hok-
University of Bologna, Bologna, Italy; Aix Marseille Univ., kaido 060-8638, Japan; Department of Diagnostic and Inter-
INSERM, INS, Inst. Neurosci. Syst., Marseille, France; APHM, ventional Radiology, Hokkaido University Graduate School of
Timone Hospital, Epileptology and Cerebral Rhythmology, Medicine, North 15, West 7, Kita-ku, Sapporo, Hokkaido 060-
Marseille, France; Aix Marseille Univ., INSERM, INS, Inst. Neu- 8638, Japan; Department of Diagnostic Radiology, Sapporo
rosci. Syst., Marseille, France; APHM, Timone Hospital, Public City General Hospital, North 11, West 13, Chuou-ku, Sapporo,
Health, Marseille, France; Aix Marseille Univ., INSERM, INS, Inst. Hokkaido 060-8604, Japan; Department of Pediatrics, Hok-
Neurosci. Syst., Marseille, France; APHM, Timone Hospital, kaido University Graduate School of Medicine, North 15, West
Epileptology and Cerebral Rhythmology, Marseille, France. 7, Kita-ku, Sapporo, Hokkaido 060-8638, Japan; Department
Electronic address: [email protected] of Child and Adolescent Psychiatry, Hokkaido University Hos-
pital, North 15, West 7, Kita-ku, Sapporo, Hokkaido 060-8638,
ABSTRACT Skin Conductance Biofeedback (SCB) is a Japan; Department of Pediatrics, Hokkaido University Gradu-
non-invasive behavioral treatment for epilepsy based ate School of Medicine, North 15, West 7, Kita-ku, Sapporo,
on modulation of Galvanic Skin Response (GSR). We Hokkaido 060-8638, Japan. Electronic address: siraisi@med.
evaluated changes in functional connectivity occurring hokudai.ac.jp
after SCB. Six patients with drug-resistant temporal
lobe epilepsy underwent monthly SCB sessions. For OBJECTIVE This study examined whether the applica-
each patient, 10 min of resting-state magnetoencepha- tion of magnetoencephalography (MEG) to interpret

 ontents  Index 164
C