Page 44 - MEGIN Book Of Abstracts - 2023

modulated functional connectivity between the FFA and typically-developing children (TDC) noted in prior
and the left IFG. The magnitude of long-range function- studies. RS MEG and structural-MRI data were obtained
al connectivity between the FFA and the inferior frontal from 51 ASD and 70 TDC 6- to 18-year-old males. PAF
gyrus was correlated with the severity of ASD. and thalamic volume maturation were observed in
TDC but not ASD. Although PAF was associated with
Keywords: autism spectrum disorder, functional connec- right thalamic volume in TDC (R[2] = 0.12, p = 0.01) but
tivity, inverted faces, phase-amplitude coupling not ASD (R[2] = 0.01, p = 0.35), this group difference
was not large enough to reach significance. Findings
Autism research: official journal of the International thus showed unusual maturation of brain function and
Society for Autism Research (2021), Vol. 14, No. 6 structure in ASD as well as an across-group thalamic
(33709531) (0 citations) contribution to alpha rhythms.

Keywords: Alpha, Autism spectrum disorder, Magnetic
Peak Alpha Frequency and Thalamic Structure in resonance imaging, Magnetoencephalography, Matura-
Children with Typical Development and Autism tion, Resting-state, Thalamic volume
Spectrum Disorder (2022)
Journal of autism and developmental disorders (2022),
Green, Heather L; Dipiero, Marissa; Koppers, Simon; Vol. 52, No. 1 (33629214) (0 citations)
Berman, Jeffrey I; Bloy, Luke; Liu, Song; McBride, Emma;
Ku, Matthew; Blaskey, Lisa; Kuschner, Emily; Airey,
Megan; Kim, Mina; Konka, Kimberly; Roberts, Timothy P Atypical spatiotemporal activation of cerebellar
L; Edgar, J Christopher lobules during emotional face processing in
adolescents with autism (2021)
Lurie Family Foundations MEG Imaging Center, Depart-
ment of Radiology, The Children's Hospital of Philadelphia, Styliadis, Charis; Leung, Rachel; Özcan, Selin; Moulton,
Philadelphia, PA, 19104, USA. [email protected]; Eric A; Pang, Elizabeth; Taylor, Margot J; Papadelis,
Developing Brain Imaging Laboratory and the Waisman Christos
Laboratory for Brain Imaging and Behavior, Neuroscience
Training Program, University of Wisconsin, Madison, WI, USA; Laboratory of Medical Physics, School of Medicine, Aristotle
Institute of Imaging and Computer Vision, RWTH Aachen University of Thessaloniki, Thessaloniki, Greece; University
University, Aachen, Germany; Department of Radiology, of Toronto, Toronto, Canada; Laboratory of Children's Brain
Perelman School of Medicine, University of Pennsylvania, Dynamics, Division of Newborn Medicine, Boston Children's
Philadelphia, USA; Clinical Psychology Program, Rowan Uni- Hospital, Harvard Medical School, Boston, Massachusetts,
versity, Glassboro, NJ, USA; Department of Nursing, University USA; Department of Ophthalmology, Boston Children's
of Pennsylvania, Philadelphia, PA, USA; Center for Autism Hospital, Harvard Medical School, Boston, Massachusetts,
Research, Department of Pediatrics, The Children's Hospital of USA; Neurosciences and Mental Health Program, Research
Philadelphia, Philadelphia, PA, USA; Department of Psychia- Institute, Hospital for Sick Children, Toronto, Canada; Autism
try, Perelman School of Medicine, University of Pennsylvania, Research Unit, Hospital for Sick Children, Toronto, Canada;
Philadelphia, PA, USA Department of Pediatrics, TCU and UNTHSC School of Medi-
cine, Fort Worth, Texas, USA
ABSTRACT Associations between age, resting-state
(RS) peak-alpha-frequency (PAF = frequency showing ABSTRACT Autism spectrum disorder (ASD) is charac-
largest amplitude alpha activity), and thalamic volume terized by social deficits and atypical facial processing
(thalamus thought to modulate alpha activity) were of emotional expressions. The underlying neuropathol-
examined to understand differences in RS alpha activity ogy of these abnormalities is still unclear. Recent stud-
between children with autism spectrum disorder (ASD) ies implicate cerebellum in emotional processing; other

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