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alography-dissociable cortical sub-areas displaying of the patients. Attenuation of neurovascular coupling
language-related activations in each of 18 patients with was found postoperatively in 17% (3 of 18) of the pa-
brain lesions and 3 healthy volunteers (during visual tients. Monohemispheric language processing cannot
language tasks). be assumed always in patients with brain lesions.
RESULTS Both modalities showed good congruency CONCLUSIONS The more detailed subdivision of
of the language areas. The mean spatial distance of language-relevant brain areas shown in this study can
the centroids and maxima was 9.06 mm and 10.58 help to achieve more radical tumor resection without
mm, respectively, allowing us to define more specific postoperative language deficits.
anatomical positions. Postoperatively, language abili-
ties increased in 11% (2 of 18) of the patients, remained Keywords: Brain tumor, Broca, Language, MEG, Reorgani-
unchanged in 83% (15 of 18) of the patients, and zation, Wernicke, fMRI
decreased in 6% (1 of 18) of the patients, respectively.
Signs of language function reorganization detected on World neurosurgery (2020), Vol. 136 (31606506) (4
both functional magnetic resonance imaging and mag- citations)
netoencephalography were present in 29% (5 of 17)
ontents Index 52
C