Page 135 - MEGIN Book Of Abstracts - 2023

seizures. We conclude that brain regions exhibiting Clinical significance of ictal
hyperperfusion during seizures highlight a preferen- magnetoencephalography in patients undergoing
tially connected interictal network, whereas regions of epilepsy surgery (2023)
ictal hypoperfusion highlight a separate, discrete and
interconnected, interictal network. Katagiri, Masaya; Wang, Z Irene; Hirfanoglu, Tugba;
Aldosari, Mubarak M; Aung, Thandar; Wang, Shan;
Keywords: MEG, SPECT, cerebral blood perfusion, epilepsy, Kobayashi, Katsuya; Bulacio, Juan; Bingaman, William;
functional connectivity Najm, Imad M; Alexopoulos, Andreas V; Burgess,
Richard C
Human brain mapping (2023), Vol. 44, No. 4 (36480260) (1
citation) Epilepsy Center, Cleveland Clinic, OH, USA; Department of
Neurosurgery, Graduate School of Medicine, Biomedical and
Health Sciences, Hiroshima University, Hiroshima, Japan;
Recording of Ictal Epileptic Activity Using on-Scalp Epilepsy Center, Cleveland Clinic, OH, USA; Department of
Magnetoencephalography (2023) Pediatric Neurology, Gazi University School of Medicine,
Ankara, Turkey; Epilepsy Center, Cleveland Clinic, OH, USA;
Feys, Odile; Corvilain, Pierre; Van Hecke, Audrey; Sculier, Epilepsy Program, National Neurosciences Institute, King
Claudine; Rikir, Estelle; Legros, Benjamin; Gaspard, Fahad Medical City, Riyadh, Saudi Arabia; Epilepsy Center,
Nicolas; Leurquin-Sterk, Gil; Holmes, Niall; Brookes, Cleveland Clinic, OH, USA; Comprehensive Epilepsy Center,
Matthew; Goldman, Serge; Wens, Vincent; De Tiège, University of Pittsburgh Medical Center, Pittsburgh, PA, USA;
Xavier Epilepsy Center, Cleveland Clinic, OH, USA; Epilepsy Center,
Department of Neurology, Second Affiliated Hospital, School
Université libre de Bruxelles (ULB), ULB Neuroscience Institute of Medicine, Zhejiang University, Hangzhou, China; Epilepsy
(UNI), Laboratoire de Neuroimagerie et Neuroanatomie Center, Cleveland Clinic, OH, USA; Department of Neurology,
translationnelles (LN2T), Brussels, Belgium; Université libre Kyoto University Graduate School of Medicine, Kyoto, Japan;
de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (HUB), Epilepsy Center, Cleveland Clinic, OH, USA. Electronic address:
Hôpital Universitaire des Enfants Reine Fabiola (HUDERF), [email protected]
Department of Pediatric Neurology, Brussels, Belgium; Univer-
sité libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles OBJECTIVE The significance of ictal magnetoencepha-
(HUB), CUB Hôpital Erasme, Department of Pediatric Neurol- lography (MEG) is not well appreciated. We evaluated
ogy, Brussels, Belgium; Université libre de Bruxelles (ULB), the relationships between ictal MEG, MRI, intracranial
Hôpital Universitaire de Bruxelles (HUB), CUB Hôpital Erasme, electroencephalography (ICEEG), surgery and postop-
Department of Neurology, Brussels, Belgium; University of erative seizure outcome.
Nottingham, School of Physics and Astronomy, Sir Peter Man-
sfield Imaging Centre, Nottingham, United Kingdom; Univer- METHODS A total of 45 patients (46 cases) with ictal
sité libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles MEG who underwent epilepsy surgery was included.
(HUB), CUB Hôpital Erasme, Department of Nuclear Medicine, We examined the localization of each modality, surgical
Brussels, Belgium; Université libre de Bruxelles (ULB), Hôpital resection area and seizure freedom after surgery.
Universitaire de Bruxelles (HUB), CUB Hôpital Erasme, Depart-
ment of Translational Neuroimaging, Brussels, Belgium RESULTS Twenty-one (45.7%) out of 46 cases were
seizure-free at more than 6 months follow-up. Median
Annals of neurology (2023), Vol. 93, No. 2 (36480016) (0 duration of postoperative follow-up was 16.5 months.
citations) The patients in whom ictal, interictal single equivalent
current dipole (SECD) and MRI lesion localization were
completely included in the resection had a higher
chance of being seizure-free significantly (p < 0.05).

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