Page 32 - MEGIN Book Of Abstracts - 2023
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Attention-Deficit Hyperactivity Disorder









            Electrophysiological Brain Changes Associated With   information on clinical symptoms was collected from
            Cognitive Improvement in a Pediatric Attention     the child´s legal guardians.
            Deficit Hyperactivity Disorder Digital Artificial
            Intelligence-Driven Intervention: Randomized       RESULTS In line with our main hypothesis, we found
            Controlled Trial (2021)                            evidence that smart, digital, cognitive treatment results
                                                               in improvements in inhibitory control performance.
                            Medina, Rafael; Bouhaben, Jaime; de Ramón, Ignacio;   Improvements were also found in visuospatial work-
            Cuesta, Pablo; Antón-Toro, Luis; Pacios, Javier; Quintero,   ing memory performance and in the cognitive flex-
            Javier; Ramos-Quiroga, Josep Antoni; Maestú, Fernando  ibility, working memory, and behavior and general
                                                               executive functioning behavioral clinical indexes in
            Sincrolab Ltd, Madrid, Spain; Faculty of Health, Camilo Jose   this group of participants. Finally, the improvements
            Cela University, Villafranca del Castillo, Spain; Radiology   found in inhibitory control were related to increases in
            Rehabilitation and Physiotherapy, Complutense University of   alpha-band power in all participants in the posterior
            Madrid, Madrid, Spain; Department of Experimental Psychol-  regions, including 2 default mode network regions of
            ogy, Faculty of Psychology, Complutense University of Madrid,   the interest: the bilateral precuneus and the bilateral
            Madrid, Spain; Department of Psychiatry, University Hospital   posterior cingulate cortex. However, only the partici-
            Infanta Leonor, Madrid, Spain; Biomedical Network Research   pants who underwent cognitive stimulation interven-
            Centre on Mental Health, Barcelona, Spain          tion (KAD_SCL_01) showed a significant increase in this
                                                               relationship.
            BACKGROUND Cognitive stimulation therapy appears
            to show promising results in the rehabilitation of im-  CONCLUSIONS The results seem to indicate that smart,
            paired cognitive processes in attention deficit hyperac-  digital treatment can be effective in the inhibitory con-
            tivity disorder.                                   trol and visuospatial working memory rehabilitation in
                                                               patients with attention deficit hyperactivity disorder.
            OBJECTIVE Encouraged by this evidence and the ever-  Furthermore, the relation of the inhibitory control with
            increasing use of technology and artificial intelligence   alpha-band power changes could mean that these
            for therapeutic purposes, we examined whether cogni-  changes are a product of plasticity mechanisms or
            tive stimulation therapy implemented on a mobile de-  changes in the neuromodulatory dynamics.
            vice and controlled by an artificial intelligence engine
            can be effective in the neurocognitive rehabilitation of   TRIAL REGISTRATION ISRCTN Registry IS-
            these patients.                                    RCTN71041318; https://www.isrctn.com/IS-
                                                               RCTN71041318.
            METHODS In this randomized study, 29 child partici-
            pants (25 males) underwent training with a smart,   Keywords: ADHD, AI, Conners continuous performance
            digital, cognitive stimulation program (KAD_SCL_01)   test, KAD_SCL_01, artificial intelligence, attention deficit
            or with 3 commercial video games for 12 weeks, 3 days   hyperactivity disorder, children, cognitive impairment,
            a week, 15 minutes a day. Participants completed a
            neuropsychological assessment and a preintervention
            and postintervention magnetoencephalography study
            in a resting state with their eyes closed. In addition,







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