Page 33 - MEGIN Book Of Abstracts - 2023

cognitive stimulation, magnetoencephalography, pediat- bands. Twenty-two ADHD patients and 23 controls
rics, rehabilitation adults were blindly randomized to two methylpheni-
date/placebo evaluation days. On each evaluation day
Journal of medical Internet research (2021), Vol. 23, No. 11 state anxiety was assessed, a 2N-back executive func-
(34842533) (4 citations) tion task was performed, and resting state MEG brain
activity was recorded at three timepoints. A frequency-
based cluster analysis yielded higher high-gamma
High-gamma oscillations as neurocorrelates of power for ADHD over posterior sensors and lower
ADHD: A MEG crossover placebo-controlled study high-gamma power for ADHD over frontal-central
(2021) sensors. These results were shown to be stable over
three measurements, unaffected by methylphenidate
Dor-Ziderman, Yair; Zeev-Wolf, Maor; Hirsch Klein, Efrat; treatment, and linked to cognitive accuracy and state
Bar-Oz, Dor; Nitzan, Uriel; Maoz, Hagai; Segev, Aviv; anxiety. Furthermore, the differential high-gamma ac-
Goldstein, Abraham; Koubi, May; Mendelovic, Shlomo; tivity evidenced substantial ADHD diagnostic efficacy,
Gvirts, Hila; Bloch, Yuval comparable to the cognitive and emotional factors.
These results indicate that resting state high-gamma
Gonda Brain Research Center, Bar Ilan University, Ramat- activity is a promising, stable, valid and diagnostically-
Gan, Israel; Edmond J. Safra Brain Research Center, University relevant neurocorrelate of ADHD. Due to the evolving
of Haifa, Haifa, Israel; Department of Education & Zlotowski understanding both in the cellular and network level
Center for Neuroscience, Ben Gurion University of the Negev, of high-gamma oscillations, focusing future studies
Israel; The Emotion-Cognition Research Center, Shalvata on this frequency band bears the potential for a better
Mental Health Care Center, Hod-Hasharon, Israel; Sackler understanding of ADHD, thus advancing the specificity
Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel; Gonda of the evaluation of the disorder and developing new
Brain Research Center, Bar Ilan University, Ramat-Gan, Israel; tools for therapy.
Department of Psychology, Bar Ilan University, Ramat-Gan,
Israel; The Emotion-Cognition Research Center, Shalvata Keywords: ADHD, High gamma, Magnetoencephalogra-
Mental Health Care Center, Hod-Hasharon, Israel; Child and phy, Methylphenidate, N-back, State anxiety
Adolescent Outpatient Clinic, Shalvata Mental Health Care
Center, Hod-Hasharon, Israel; Sackler Faculty of Medicine, Journal of psychiatric research (2021), Vol. 137 (33684643)
Tel-Aviv University, Tel-Aviv, Israel; Department of Behavioral (1 citation)
Sciences and Psychology, Ariel University, Ariel, Israel; The
Emotion-Cognition Research Center, Shalvata Mental Health
Care Center, Hod-Hasharon, Israel; Child and Adolescent Out- Characterizing Inscapes and resting-state in MEG:
patient Clinic, Shalvata Mental Health Care Center, Hod-Ha- Effects in typical and atypical development (2021)
sharon, Israel; Sackler Faculty of Medicine, Tel-Aviv University,
Tel-Aviv, Israel. Electronic address: [email protected] Vandewouw, Marlee M; Dunkley, Benjamin T; Lerch,
Jason P; Anagnostou, Evdokia; Taylor, Margot J
ABSTRACT Attention Deficit Hyperactive Disorder
(ADHD) is a common neurobehavioral disorder with Department of Diagnostic Imaging, Hospital for Sick
a significant and pervasive impact on patients' lives. Children, 555 University Ave, Toronto, ON M5G 1X8, Canada;
Identifying neurophysiological correlates of ADHD is Program in Neurosciences and Mental Health, Hospital for
important for understanding its underlying mecha- Sick Children, Toronto, Canada; Autism Research Centre,
nisms, as well as for improving clinical accuracy beyond Bloorview Research Institute, Holland Bloorview Kids Reha-
cognitive and emotional factors. The present study bilitation Hospital, Toronto, ON, Canada; Institute of Biomedi-
focuses on finding a diagnostic stable neural corre- cal Engineering, University of Toronto, Toronto, Canada.
late based on evaluating MEG resting state frequency Electronic address: [email protected]; Depart-

 ontents  Index 12
C