Page 36 - MEGIN Book Of Abstracts - 2023

Canada; Vector Institute for Artificial Intelligence, Toronto, Keywords: Autism, Electroencephalography, Machine
ON, Canada; Cognitive Neuroscience Unit, School of Psychol- learning, Magnetoencephalography, Neurophysiology,
ogy, Deakin University, Geelong, Australia; Insitute for Health Review, Support vector machines, Systematic
and Sport, Victoria University, Melbourne, Australia; Centre for
Addiction and Mental Health, Toronto, Canada; Department Progress in neuro-psychopharmacology & biological
of Psychiatry, University of Toronto, Toronto, ON, Canada; psychiatry (2023), Vol. 123 (36574922) (0 citations)
Temerty Centre for Therapeutic Brain Intervention, Centre
for Addiction and Mental Health, Toronto, ON, Canada;
Centre for Addiction and Mental Health, Toronto, Canada; Neuromagnetic 40 Hz Auditory Steady-State
Department of Psychiatry, University of Toronto, Toronto, ON, Response in the left auditory cortex is related to
Canada; Azrieli Adult Neurodevelopmental Centre, Centre for language comprehension in children with Autism
Addiction and Mental Health, Toronto, ON, Canada; Temerty Spectrum Disorder (2023)
Centre for Therapeutic Brain Intervention, Centre for Addic-
tion and Mental Health, Toronto, ON, Canada. Electronic Arutiunian, Vardan; Arcara, Giorgio; Buyanova, Irina;
address: [email protected] Davydova, Elizaveta; Pereverzeva, Darya; Sorokin,
Alexander; Tyushkevich, Svetlana; Mamokhina, Uliana;
ABSTRACT There are growing application of machine Danilina, Kamilla; Dragoy, Olga
learning models to study the intricacies of non-linear
and non-stationary characteristics of electroencepha- Center for Language and Brain, HSE University, Moscow,
lography (EEG) and magnetoencephalography (MEG) Russia. Electronic address: [email protected];
data in neurobiologically complex and heterogeneous IRCCS San Camillo Hospital, Venice, Italy; Federal Resource
conditions such as autism spectrum disorder (ASD). Center for ASD, Moscow State University of Psychology and
Such tools have potential diagnostic applications, and Education, Moscow, Russia; Chair of Differential Psychology
given the highly heterogeneous presentation of ASD, and Psychophysiology, Moscow State University of Psychol-
might prove fruitful in early detection and therefore ogy and Education, Moscow, Russia; Federal Resource Center
could facilitate very early intervention. We conducted for ASD, Moscow State University of Psychology and Educa-
a systematic review (PROSPERO ID#CRD42021257438) tion, Moscow, Russia; Haskins Laboratories, New Haven, CT,
by searching PubMed, EMBASE, and PsychINFO for ma- United States of America; Center for Language and Brain, HSE
chine learning approaches for EEG and MEG analyses University, Moscow, Russia; Institute of Linguistics, Russian
in ASD. Thirty-nine studies were identified, of which Academy of Sciences, Moscow, Russia
the majority (18) used support vector machines for
classification; other successful methods included deep ABSTRACT Language impairment is comorbid in most
learning. Thirty-seven studies were found to employ children with Autism Spectrum Disorder (ASD), but its
EEG and two were found to employ MEG. This system- neural mechanisms are still poorly understood. Some
atic review indicate that machine learning methods studies hypothesize that the atypical low-level sensory
can be used to classify ASD, predict ASD diagnosis in perception in the auditory cortex accounts for the
high-risk infants as early as 3 months of age, predict abnormal language development in these children.
ASD symptom severity, and classify states of cognition One of the potential non-invasive measures of such
in ASD with high accuracy. Replication studies testing low-level perception can be the cortical gamma-band
validity, reproducibility and generalizability in tandem oscillations registered with magnetoencephalography
with randomized controlled trials in ASD populations (MEG), and 40 Hz Auditory Steady-State Response
will likely benefit the field. (40 Hz ASSR) is a reliable paradigm for eliciting auditory
gamma response. Although there is research in chil-
dren with and without ASD using 40 Hz ASSR, nothing
is known about the relationship between this audi-
tory response in children with ASD and their language

 ontents  Index 15
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